Wednesday, July 17, 2013
Rat Cardiac Myocytes
This video shows the changes in optical thickness (OT) of spontaneously beating rat cardiac myocytes as imaged with the BioCam Quantitative Phase Microscope. The myocytes were measured in a Bioptechs FCS3 perfusion chamber with an aluminized base plate and a 100μm gasket. Cells were kept at 37°C with an HBSS (Hank’s balanced salt solution) fluid bath. The video on the left shows a 2D representation of the OT data, while the video at right shows the data in 3D. The maps were acquired at 15fps.
Tuesday, July 9, 2013
Successful survey prompts product release plans
Thanks to everyone who participated in the "New Directions in Live Cell & Tissue Imaging" survey at microscopyeducation.com.
Congratulations to Scott Russell of the Noble Microscopy Lab at the
University of Oklahoma, who won our drawing for the the Bose Wave III
Radio and iPod docking station!
Over 340 of you provided valuable feedback regarding this intriguing new technology. Many of you also expressed interest in becoming beta sites for the technology.
Due to the overwhelmingly positive feedback from the survey 4D Technology is proceeding with the commercialization of this technology. 4D has a long history of creating successful products based on novel interferometric technologies. The new BioCam Quantitative Phase Microscope will extend the usefulness of these techniques into bioscience applications.
As you learned from the survey, our phase imaging technology measures optical topography along with variations in optical thickness of living cells and tissues. The BioCam will allow researchers to rapidly map and quantify optical thickness, acquiring dimensional and volumetric information at a rate of 15 frames/second, without perturbing living cells or requiring fixed material. This data provides valuable information for cellular dynamics, motility, and cell and tissue morphology.
If you have an application that you would like to test with this new technology, please let us know. We are also looking for development partners who would like to help us further our work in specific application areas and who want to explore the uniqueness of this new technology.
If you are interested in more information on the BioCam Quantitative Phase Microscopeor interested in becoming a beta site, or if you know someone who would be interested in this technology, please contact Kathy Creath, Principal Investigator for the project, at kathy.creath@4dtechnology.com or (520) 294-5600 x211. You can also connect with Dr. Creath on LinkedIn.
Over 340 of you provided valuable feedback regarding this intriguing new technology. Many of you also expressed interest in becoming beta sites for the technology.
Due to the overwhelmingly positive feedback from the survey 4D Technology is proceeding with the commercialization of this technology. 4D has a long history of creating successful products based on novel interferometric technologies. The new BioCam Quantitative Phase Microscope will extend the usefulness of these techniques into bioscience applications.
As you learned from the survey, our phase imaging technology measures optical topography along with variations in optical thickness of living cells and tissues. The BioCam will allow researchers to rapidly map and quantify optical thickness, acquiring dimensional and volumetric information at a rate of 15 frames/second, without perturbing living cells or requiring fixed material. This data provides valuable information for cellular dynamics, motility, and cell and tissue morphology.
BioCam Phase Imaging Microscope
If you have an application that you would like to test with this new technology, please let us know. We are also looking for development partners who would like to help us further our work in specific application areas and who want to explore the uniqueness of this new technology.
If you are interested in more information on the BioCam Quantitative Phase Microscopeor interested in becoming a beta site, or if you know someone who would be interested in this technology, please contact Kathy Creath, Principal Investigator for the project, at kathy.creath@4dtechnology.com or (520) 294-5600 x211. You can also connect with Dr. Creath on LinkedIn.
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